It is a hair condition that frustrates parents for decades. Now scientists think they have the answer. genes responsibleUncombable hair syndrome. It is true.
Uncombable hair syndrome can be more than difficult hair. This is hair that sticks out at every angle, and it can be difficult to tame, let alone comb.
It is usually seen in children aged between three and twelve years old. It is characterized by a straw-blond or silvery-blond frizzy look. It is usually dry, brittle, and wavy. Sometimes, spun glass hair is referred to because of its appearance. pili trianguli et canaliculiOr cheveux incoiffables.
Boris JohnsonOr Albert EinsteinIt might be a thought that comes to mind. However, while celebrities are known for their unruly hair, there are very few cases of uncombable scalp syndrome worldwide. It is also common for the condition to disappear or improve with age.
Although this rare condition is still understudied, it was first reported in published articles. In the 1970s. There have been fewer than 70 publications since then, the majority being case reports.
One of the most recent studiesGeneticists from the University of Bonn in Germany conducted a study on 11 children with uncombable hair. The geneticists at the University of Bonn, Germany found that the condition was explained by mutations in three genes coding for well-known proteins within the hair follicle.
Since the study was widely covered by the media, many more families came forward with children with the condition. Scientists have now repeated the genetics on over 100 children. They confirmed that the cause of hair-fibre loss was found in 76 of the children.
Variation in human appearance, including hair color, can be attributed to genetic variations within the global population.
Sometimes, a mutation can cause a change to the function of a protein. The hair may look different if the protein is found in the hair’s follicle. You can have brown, blonde, curly hair, straight, red hair, or even bald.
Although there are a few known inherited variations in hair curl and shape, they are not often linked to serious diseases. The proteins most affected are often found in the inner root sheath, which is three layers of hair follicles that shape the hair fibre.
Recessive genes
Uncombable hair is also a genetic characteristic. This means that both parents must have the affected gene. If their child inherits one copy from each parent with the affected gene, the syndrome will be passed to them.
Why study genetic hair disorders like this? This type of genetic research generates enough information so that parents can request a test that might help address any concerns. Other rare conditionsIt can also affect hair.
The scientific perspective also allows the hair biology community to learn more about normal hair development and the importance different proteins for controlling hair appearance. We can now understand how PADI3 works in the hair follicle and explain why it might affect hair shape.
One of the most culturally unique and personal characteristics is hair. Everyone thinks about hair every day. The last century has seen the development of a large hair-care industry to help us all manage hair.
When a rare condition causes a remarkable, but difficult-to-manage change in hair, scientists can see why it is important to understand the process and help families who have children affected.
Gill WestgateFaculty of Life Sciences Business Development Manager University of Bradford.
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