The levels of caffeineThe amount of fat in your body could be affected by the level of cholesterol in your blood. This could then determine your risk for developing type 2. DiabetesCardiovascular diseases are among the most common.
These are the results of a recent genetic marker-based study, which established a definitive link between BMI and type-2 diabetes risk.
The team of researchers from the Karolinska in Sweden, University of Bristol and Imperial College London said that caffeine-free drinks may be explored to help reduce body weight.
Researchers found that higher levels of plasma caffeine were predicted to be associated with lower body mass index and BMI. WriterTheir paper was published in March.
Further, higher caffeine plasma concentrations predicted genetically were associated with a reduced risk of type 2 diabetics. It was estimated that caffeine reduced type 2 diabetes risk by approximately half.
This study collected data on just under 10 000 people from existing genetic databases and focused on vVariations near or in specific genes are known to influence the rate at which caffeine breaks down..
In general, those who have variations that affect the genes – namely CYP1A2 and a gene that regulates it, called AHR – tend to break caffeine down more slowly, allowing it to remain in the blood longer. Yet, they tend to drink less coffee in general.
An approach called Mendelian randomizationIt is used to deterMine likely causal relationships between the existence of variations, illnesses such as diabetes, body mass and lifestyle factors.
Although there was a significant correlation between caffeine levels and BMI in relation to type 2 diabetic risk, the amount of coffee in the blood did not appear to be associated with cardiovascular diseases, including stroke, atrial fibrillation or heart failure.
In previous studies, a moderate increase in caffeine consumption was linked to an increased risk of heart disease. better heart healthThe following are some examples of how to get started: a lower BMIThe new research provides more details about what we know already about the effects of CoffeeHas on the body.
Keep in mind also the effects that caffeine has on the body All positive isn’t always the caseWhat is meant by? Attention must be paid when weighing up the benefits of drinking it – but this latest study is an important step in assessing how much caffeine is ideal.
The researchers said that although short-term studies have shown weight loss and fat mass reduction with caffeine intake, the effects on the body over the long term are not known. You can learn more about this by clicking here..
The team believes that the association here may be because caffeine increases thermogenesis in the body (heating up) and fat oxidation in the body (turning fatty acids into energy), which are both important in metabolism.
Further research will be required to confirm cause-and effect. Although this study used a large population, Mendelian Randomization is not infallible. Other factors may be at play and were not accounted for.
Even small metabolic effects of caffeine could have significant health implications, considering the widespread consumption of caffeine around the world. The researchers wrote.
The research was published by BMJ Medicine.
This article was first published in March 2023.
